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Αβ Hinders Nuclear Targeting of AICD and Fe65 in Primary Neuronal Cultures
The intracellular domain of the Alzheimer’s amyloid precursor protein (AICD) has been described as an important player in the transactivation of specific genes. It results from proteolytic processing of the Alzheimer’s amyloid precursor protein (APP), as does the neurotoxic Aβ peptide. Although norm...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Humana Press Inc
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744832/ https://www.ncbi.nlm.nih.gov/pubmed/19340611 http://dx.doi.org/10.1007/s12031-009-9192-9 |