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Αβ Hinders Nuclear Targeting of AICD and Fe65 in Primary Neuronal Cultures

The intracellular domain of the Alzheimer’s amyloid precursor protein (AICD) has been described as an important player in the transactivation of specific genes. It results from proteolytic processing of the Alzheimer’s amyloid precursor protein (APP), as does the neurotoxic Aβ peptide. Although norm...

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Detalles Bibliográficos
Autores principales: Henriques, A. G., Vieira, S. I., da Cruz e Silva, E. F., da Cruz e Silva, O. A. B.
Formato: Texto
Lenguaje:English
Publicado: Humana Press Inc 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744832/
https://www.ncbi.nlm.nih.gov/pubmed/19340611
http://dx.doi.org/10.1007/s12031-009-9192-9