Engineering and validation of a novel lipid thin film for biomembrane modeling in lipophilicity determination of drugs and xenobiotics

BACKGROUND: Determination of lipophilicity as a tool for predicting pharmacokinetic molecular behavior is limited by the predictive power of available experimental models of the biomembrane. There is current interest, therefore, in models that accurately simulate the biomembrane structure and functi...

Descripción completa

Detalles Bibliográficos
Autores principales: Idowu, Sunday Olakunle, Adeyemo, Morenikeji Ambali, Ogbonna, Udochi Ihechiluru
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745359/
https://www.ncbi.nlm.nih.gov/pubmed/19735551
http://dx.doi.org/10.1186/1754-1611-3-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745359/
https://www.ncbi.nlm.nih.gov/pubmed/19735551
http://dx.doi.org/10.1186/1754-1611-3-14

Ejemplares similares