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Engineering and validation of a novel lipid thin film for biomembrane modeling in lipophilicity determination of drugs and xenobiotics
BACKGROUND: Determination of lipophilicity as a tool for predicting pharmacokinetic molecular behavior is limited by the predictive power of available experimental models of the biomembrane. There is current interest, therefore, in models that accurately simulate the biomembrane structure and functi...
Autores principales: | Idowu, Sunday Olakunle, Adeyemo, Morenikeji Ambali, Ogbonna, Udochi Ihechiluru |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745359/ https://www.ncbi.nlm.nih.gov/pubmed/19735551 http://dx.doi.org/10.1186/1754-1611-3-14 |
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