Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARγ stimulation

BACKGROUND: Type 2 diabetes mellitus (T2DM) is commonly associated with both microvascular and macrovascular complications and a strong correlation exists between glycaemic control and the incidence and progression of vascular complications. Pioglitazone, a Peroxisome proliferator-activated receptor...

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Detalles Bibliográficos
Autores principales: Biscetti, Federico, Straface, Giuseppe, Arena, Vincenzo, Stigliano, Egidio, Pecorini, Giovanni, Rizzo, Paola, De Angelis, Giulia, Iuliano, Luigi, Ghirlanda, Giovanni, Flex, Andrea
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745363/
https://www.ncbi.nlm.nih.gov/pubmed/19737384
http://dx.doi.org/10.1186/1475-2840-8-49

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745363/
https://www.ncbi.nlm.nih.gov/pubmed/19737384
http://dx.doi.org/10.1186/1475-2840-8-49

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