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Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis

BACKGROUND: Glucocorticoid hormones (GCs) induce apoptosis of leukemic T-cells by transcriptional regulation via the GC receptor, GR. In the human leukemic CEM cell culture model, RCAN1 has been identified as one of the genes that is specifically upregulated only in the GC-sensitive CEM C7-14 cells,...

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Detalles Bibliográficos
Autores principales: Hirakawa, Yasuko, Nary, Laura J, Medh, Rheem D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745384/
https://www.ncbi.nlm.nih.gov/pubmed/19725972
http://dx.doi.org/10.1186/1750-2187-4-6