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The ordering of expression among a few genes can provide simple cancer biomarkers and signal BRCA1 mutations

BACKGROUND: A major challenge in computational biology is to extract knowledge about the genetic nature of disease from high-throughput data. However, an important obstacle to both biological understanding and clinical applications is the "black box" nature of the decision rules provided b...

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Detalles Bibliográficos
Autores principales: Lin, Xue, Afsari, Bahman, Marchionni, Luigi, Cope, Leslie, Parmigiani, Giovanni, Naiman, Daniel, Geman, Donald
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745389/
https://www.ncbi.nlm.nih.gov/pubmed/19695104
http://dx.doi.org/10.1186/1471-2105-10-256