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The ordering of expression among a few genes can provide simple cancer biomarkers and signal BRCA1 mutations
BACKGROUND: A major challenge in computational biology is to extract knowledge about the genetic nature of disease from high-throughput data. However, an important obstacle to both biological understanding and clinical applications is the "black box" nature of the decision rules provided b...
Autores principales: | Lin, Xue, Afsari, Bahman, Marchionni, Luigi, Cope, Leslie, Parmigiani, Giovanni, Naiman, Daniel, Geman, Donald |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745389/ https://www.ncbi.nlm.nih.gov/pubmed/19695104 http://dx.doi.org/10.1186/1471-2105-10-256 |
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