Rac1 activation inhibits E-cadherin-mediated adherens junctions via binding to IQGAP1 in pancreatic carcinoma cells

BACKGROUND: Monomeric GTPases of the Rho family control a variety of cellular functions including actin cytoskeleton organisation, cell migration and cell adhesion. Defects in these regulatory processes are involved in tumour progression and metastasis. The development of metastatic carcinoma is acc...

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Detalles Bibliográficos
Autores principales: Hage, Beatrix, Meinel, Katrin, Baum, Iris, Giehl, Klaudia, Menke, Andre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745413/
https://www.ncbi.nlm.nih.gov/pubmed/19737400
http://dx.doi.org/10.1186/1478-811X-7-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745413/
https://www.ncbi.nlm.nih.gov/pubmed/19737400
http://dx.doi.org/10.1186/1478-811X-7-23

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