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Protective effect of transgenic expression of porcine heat shock protein 70 on hypothalamic ischemic and oxidative damage in a mouse model of heatstroke

BACKGROUND: Transgenic mice have been used to examine the role of heat shock protein (HSP)72 in experimental heatstroke. Transgenic mice that were heterozygous for a porcine HSP70β gene ([+] HSP72) and transgene-negative littermate controls ([-] HSP72), under pentobarbital sodium anesthesia, were su...

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Detalles Bibliográficos
Autores principales: Chen, Zhih-Cherng, Wu, Wen-Shian, Lin, Mao-Tsun, Hsu, Chuan-Chih
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745415/
https://www.ncbi.nlm.nih.gov/pubmed/19725984
http://dx.doi.org/10.1186/1471-2202-10-111