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Adenoviral Mediated, Intra-Tumor Gene Transfer of Interleukin 23 Induces a Therapeutic Anti-tumor Response

IL-23 is a member of the IL-12 family of heterodimeric cytokines, comprised of p19 and p40 subunits, which exhibits immunostimulatory properties similar to IL-12. IL-23 has been shown to possess potent anti-tumor activities in several establishment models of cancer and a few therapeutic models, but...

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Detalles Bibliográficos
Autores principales: Reay, Ja'Nean, Kim, Seon-Hee, Lockhart, Euan, Kolls, Jay, Robbins, Paul D.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745505/
https://www.ncbi.nlm.nih.gov/pubmed/19390568
http://dx.doi.org/10.1038/cgt.2009.27