Cargando…

RNase L Mediated Protection from Virus Induced Demyelination

IFN-α/β plays a critical role in limiting viral spread, restricting viral tropism and protecting mice from neurotropic coronavirus infection. However, the IFN-α/β dependent mechanisms underlying innate anti-viral functions within the CNS are poorly understood. The role of RNase L in viral encephalom...

Descripción completa

Detalles Bibliográficos
Autores principales: Ireland, Derek D. C., Stohlman, Stephen A., Hinton, David R., Kapil, Parul, Silverman, Robert H., Atkinson, Roscoe A., Bergmann, Cornelia C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745574/
https://www.ncbi.nlm.nih.gov/pubmed/19798426
http://dx.doi.org/10.1371/journal.ppat.1000602