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RNase L Mediated Protection from Virus Induced Demyelination

IFN-α/β plays a critical role in limiting viral spread, restricting viral tropism and protecting mice from neurotropic coronavirus infection. However, the IFN-α/β dependent mechanisms underlying innate anti-viral functions within the CNS are poorly understood. The role of RNase L in viral encephalom...

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Detalles Bibliográficos
Autores principales:	Ireland, Derek D. C., Stohlman, Stephen A., Hinton, David R., Kapil, Parul, Silverman, Robert H., Atkinson, Roscoe A., Bergmann, Cornelia C.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745574/ https://www.ncbi.nlm.nih.gov/pubmed/19798426 http://dx.doi.org/10.1371/journal.ppat.1000602

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