Pairwise and higher-order correlations among drug-resistance mutations in HIV-1 subtype B protease

BACKGROUND: The reaction of HIV protease to inhibitor therapy is characterized by the emergence of complex mutational patterns which confer drug resistance. The response of HIV protease to drugs often involves both primary mutations that directly inhibit the action of the drug, and a host of accesso...

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Detalles Bibliográficos
Autores principales: Haq, Omar, Levy, Ronald M, Morozov, Alexandre V, Andrec, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745583/
https://www.ncbi.nlm.nih.gov/pubmed/19758465
http://dx.doi.org/10.1186/1471-2105-10-S8-S10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745583/
https://www.ncbi.nlm.nih.gov/pubmed/19758465
http://dx.doi.org/10.1186/1471-2105-10-S8-S10

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