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Pairwise and higher-order correlations among drug-resistance mutations in HIV-1 subtype B protease
BACKGROUND: The reaction of HIV protease to inhibitor therapy is characterized by the emergence of complex mutational patterns which confer drug resistance. The response of HIV protease to drugs often involves both primary mutations that directly inhibit the action of the drug, and a host of accesso...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745583/ https://www.ncbi.nlm.nih.gov/pubmed/19758465 http://dx.doi.org/10.1186/1471-2105-10-S8-S10 |