Correlating protein function and stability through the analysis of single amino acid substitutions

BACKGROUND: Mutations resulting in the disruption of protein function are the underlying causes of many genetic diseases. Some mutations affect the number of expressed proteins while others alter the activity on a per-molecule basis. Single amino acid substitutions as caused by non-synonymous Single...

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Detalles Bibliográficos
Autores principales: Bromberg, Yana, Rost, Burkhard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745590/
https://www.ncbi.nlm.nih.gov/pubmed/19758472
http://dx.doi.org/10.1186/1471-2105-10-S8-S8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745590/
https://www.ncbi.nlm.nih.gov/pubmed/19758472
http://dx.doi.org/10.1186/1471-2105-10-S8-S8

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