Cargando…
Correlating protein function and stability through the analysis of single amino acid substitutions
BACKGROUND: Mutations resulting in the disruption of protein function are the underlying causes of many genetic diseases. Some mutations affect the number of expressed proteins while others alter the activity on a per-molecule basis. Single amino acid substitutions as caused by non-synonymous Single...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745590/ https://www.ncbi.nlm.nih.gov/pubmed/19758472 http://dx.doi.org/10.1186/1471-2105-10-S8-S8 |