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TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP

Transient receptor potential V3 (TRPV3) and TRPV4 are heat-activated cation channels expressed in keratinocytes. It has been proposed that heat-activation of TRPV3 and/or TRPV4 in the skin may release diffusible molecules which would then activate termini of neighboring dorsal root ganglion (DRG) ne...

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Detalles Bibliográficos
Autores principales: Mandadi, Sravan, Sokabe, Takaaki, Shibasaki, Koji, Katanosaka, Kimiaki, Mizuno, Atsuko, Moqrich, Aziz, Patapoutian, Ardem, Fukumi-Tominaga, Tomoko, Mizumura, Kazue, Tominaga, Makoto
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745623/
https://www.ncbi.nlm.nih.gov/pubmed/19669158
http://dx.doi.org/10.1007/s00424-009-0703-x