Genetic Variation in the Familial Mediterranean Fever Gene (MEFV) and Risk for Crohn's Disease and Ulcerative Colitis

BACKGROUND AND AIMS: The familial Mediterranean fever (FMF) gene (MEFV) encodes pyrin, a major regulator of the inflammasome platform controlling caspase-1 activation and IL-1β processing. Pyrin has been shown to interact with the gene product of NLRP3, NALP3/cryopyrin, also an important active memb...

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Detalles Bibliográficos
Autores principales: Villani, Alexandra-Chloé, Lemire, Mathieu, Louis, Edouard, Silverberg, Mark S., Collette, Catherine, Fortin, Geneviève, Nimmo, Elaine R., Renaud, Yannick, Brunet, Sébastien, Libioulle, Cécile, Belaiche, Jacques, Bitton, Alain, Gaudet, Daniel, Cohen, Albert, Langelier, Diane, Rioux, John D., Arnott, Ian D. R., Wild, Gary E., Rutgeerts, Paul, Satsangi, Jack, Vermeire, Séverine, Hudson, Thomas J., Franchimont, Denis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745755/
https://www.ncbi.nlm.nih.gov/pubmed/19784369
http://dx.doi.org/10.1371/journal.pone.0007154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745755/
https://www.ncbi.nlm.nih.gov/pubmed/19784369
http://dx.doi.org/10.1371/journal.pone.0007154

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