Assisted assembly: how to improve a de novo genome assembly by using related species

We describe a new assembly algorithm, where a genome assembly with low sequence coverage, either throughout the genome or locally, due to cloning bias, is considerably improved through an assisting process via a related genome. We show that the information provided by aligning the whole-genome shotg...

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Detalles Bibliográficos
Autores principales: Gnerre, Sante, Lander, Eric S, Lindblad-Toh, Kerstin, Jaffe, David B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745769/
https://www.ncbi.nlm.nih.gov/pubmed/19712469
http://dx.doi.org/10.1186/gb-2009-10-8-r88

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745769/
https://www.ncbi.nlm.nih.gov/pubmed/19712469
http://dx.doi.org/10.1186/gb-2009-10-8-r88

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