Increased production of soluble CTLA-4 in patients with spondylarthropathies correlates with disease activity

INTRODUCTION: Spondylarthropathies (SpA) are characterized by abnormal immune responses including T cell activation. Cytotoxic T lymphocyte associated molecule-4 (CTLA-4) is involved in down-regulating immune responses. A soluble form of CTLA-4 (sCTLA-4), resulting from an alternative splicing, has...

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Detalles Bibliográficos
Autores principales: Toussirot, Éric, Saas, Philippe, Deschamps, Marina, Pouthier, Fabienne, Perrot, Lucille, Perruche, Sylvain, Chabod, Jacqueline, Tiberghien, Pierre, Wendling, Daniel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745776/
https://www.ncbi.nlm.nih.gov/pubmed/19570209
http://dx.doi.org/10.1186/ar2747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745776/
https://www.ncbi.nlm.nih.gov/pubmed/19570209
http://dx.doi.org/10.1186/ar2747

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