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Increased production of soluble CTLA-4 in patients with spondylarthropathies correlates with disease activity

INTRODUCTION: Spondylarthropathies (SpA) are characterized by abnormal immune responses including T cell activation. Cytotoxic T lymphocyte associated molecule-4 (CTLA-4) is involved in down-regulating immune responses. A soluble form of CTLA-4 (sCTLA-4), resulting from an alternative splicing, has...

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Detalles Bibliográficos
Autores principales:	Toussirot, Éric, Saas, Philippe, Deschamps, Marina, Pouthier, Fabienne, Perrot, Lucille, Perruche, Sylvain, Chabod, Jacqueline, Tiberghien, Pierre, Wendling, Daniel
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745776/ https://www.ncbi.nlm.nih.gov/pubmed/19570209 http://dx.doi.org/10.1186/ar2747

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