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Increased production of soluble CTLA-4 in patients with spondylarthropathies correlates with disease activity
INTRODUCTION: Spondylarthropathies (SpA) are characterized by abnormal immune responses including T cell activation. Cytotoxic T lymphocyte associated molecule-4 (CTLA-4) is involved in down-regulating immune responses. A soluble form of CTLA-4 (sCTLA-4), resulting from an alternative splicing, has...
Autores principales: | Toussirot, Éric, Saas, Philippe, Deschamps, Marina, Pouthier, Fabienne, Perrot, Lucille, Perruche, Sylvain, Chabod, Jacqueline, Tiberghien, Pierre, Wendling, Daniel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745776/ https://www.ncbi.nlm.nih.gov/pubmed/19570209 http://dx.doi.org/10.1186/ar2747 |
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