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Analysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid diseases

INTRODUCTION: The majority of autoimmune diseases such as rheumatoid arthritis (RA) and autoimmune thyroid diseases (AITDs) are characterized by a striking female predominance superimposed on a predisposing genetic background. The role of extremely skewed X-chromosome inactivation (XCI) has been que...

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Detalles Bibliográficos
Autores principales: Chabchoub, Ghazi, Uz, Elif, Maalej, Abdellatif, Mustafa, Chigdem A, Rebai, Ahmed, Mnif, Mouna, Bahloul, Zouheir, Farid, Nadir R, Ozcelik, Tayfun, Ayadi, Hammadi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745787/
https://www.ncbi.nlm.nih.gov/pubmed/19589151
http://dx.doi.org/10.1186/ar2759