Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus

INTRODUCTION: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of high-titer IgG autoantibodies directed against nuclear autoantigens. Type I interferon (IFN-I) has been shown to play a pathogenic role in this disease. In the current study, we charac...

Descripción completa

Detalles Bibliográficos
Autores principales: Thibault, Donna L, Graham, Kareem L, Lee, Lowen Y, Balboni, Imelda, Hertzog, Paul J, Utz, Paul J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745794/
https://www.ncbi.nlm.nih.gov/pubmed/19624844
http://dx.doi.org/10.1186/ar2771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745794/
https://www.ncbi.nlm.nih.gov/pubmed/19624844
http://dx.doi.org/10.1186/ar2771

Ejemplares similares