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Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus

INTRODUCTION: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of high-titer IgG autoantibodies directed against nuclear autoantigens. Type I interferon (IFN-I) has been shown to play a pathogenic role in this disease. In the current study, we charac...

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Detalles Bibliográficos
Autores principales:	Thibault, Donna L, Graham, Kareem L, Lee, Lowen Y, Balboni, Imelda, Hertzog, Paul J, Utz, Paul J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745794/ https://www.ncbi.nlm.nih.gov/pubmed/19624844 http://dx.doi.org/10.1186/ar2771

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