Immunization with an immunodominant self-peptide derived from glucose-6-phosphate isomerase induces arthritis in DBA/1 mice

INTRODUCTION: T-helper (Th) lymphocytes are critically required for the pathogenesis of glucose-6-phosphate isomerase (G6PI)-induced arthritis, but neither the G6PI epitopes recognized by arthritogenic T cells nor their pathogenic effector functions have been fully elucidated to date. We aimed at id...

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Detalles Bibliográficos
Autores principales: Bruns, Lisa, Frey, Oliver, Morawietz, Lars, Landgraf, Christiane, Volkmer, Rudolf, Kamradt, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745800/
https://www.ncbi.nlm.nih.gov/pubmed/19640302
http://dx.doi.org/10.1186/ar2777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745800/
https://www.ncbi.nlm.nih.gov/pubmed/19640302
http://dx.doi.org/10.1186/ar2777

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