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Immunization with an immunodominant self-peptide derived from glucose-6-phosphate isomerase induces arthritis in DBA/1 mice
INTRODUCTION: T-helper (Th) lymphocytes are critically required for the pathogenesis of glucose-6-phosphate isomerase (G6PI)-induced arthritis, but neither the G6PI epitopes recognized by arthritogenic T cells nor their pathogenic effector functions have been fully elucidated to date. We aimed at id...
Autores principales: | Bruns, Lisa, Frey, Oliver, Morawietz, Lars, Landgraf, Christiane, Volkmer, Rudolf, Kamradt, Thomas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745800/ https://www.ncbi.nlm.nih.gov/pubmed/19640302 http://dx.doi.org/10.1186/ar2777 |
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