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UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways

The UNC-5 receptor mediates axon repulsion from UNC-6/netrin through UNC-40 dependent (‘UNC-5+UNC-40’) and independent (‘UNC-5-alone’) signaling pathways. A requirement for UNC-40 dependent signaling has been shown in long-range repulsion from UNC-6/netrin, however, the mechanisms used to regulate d...

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Detalles Bibliográficos
Autores principales: MacNeil, Lesley T., Hardy, W. Rod, Pawson, Tony, Wrana, Jeffrey L., Culotti, Joseph G.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745997/
https://www.ncbi.nlm.nih.gov/pubmed/19169249
http://dx.doi.org/10.1038/nn.2256