Cargando…

UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways

The UNC-5 receptor mediates axon repulsion from UNC-6/netrin through UNC-40 dependent (‘UNC-5+UNC-40’) and independent (‘UNC-5-alone’) signaling pathways. A requirement for UNC-40 dependent signaling has been shown in long-range repulsion from UNC-6/netrin, however, the mechanisms used to regulate d...

Descripción completa

Detalles Bibliográficos
Autores principales:	MacNeil, Lesley T., Hardy, W. Rod, Pawson, Tony, Wrana, Jeffrey L., Culotti, Joseph G.
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745997/ https://www.ncbi.nlm.nih.gov/pubmed/19169249 http://dx.doi.org/10.1038/nn.2256

Ejemplares similares

The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP
por: Norris, Adam D., et al.
Publicado: (2014)

UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity
por: Wang, Zheng, et al.
Publicado: (2014)

Experimental evidence for UNC-6 (netrin) axon guidance by stochastic fluctuations of intracellular UNC-40 (DCC) outgrowth activity
por: Kulkarni, Gauri, et al.
Publicado: (2013)

UNC-116 and UNC-16 function with the NEKL-3 kinase to promote axon targeting
por: Drozd, Cody J., et al.
Publicado: (2023)

Extracellular Matrix Regulates UNC-6 (Netrin) Axon Guidance by Controlling the Direction of Intracellular UNC-40 (DCC) Outgrowth Activity
por: Yang, Yong, et al.
Publicado: (2014)

The Caenorhabditis elegans voltage-gated calcium channel subunits UNC-2 and UNC-36 and the calcium-dependent kinase UNC-43/CaMKII regulate neuromuscular junction morphology
por: Caylor, Raymond C, et al.
Publicado: (2013)

Two alleles of unc-52 locus disrupting potential cell-binding motif of UNC-52
por: Wilsey, Rachel, et al.
Publicado: (2020)

unc-119 mutants have an increased fungal spore adhesion that is not rescued by Cb-unc-119
por: Omi, Shizue, et al.
Publicado: (2021)

Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila
por: Pooryasin, Atefeh, et al.
Publicado: (2021)

Structure and mechanism of NALCN-FAM155A-UNC79-UNC80 channel complex
por: Kang, Yunlu, et al.
Publicado: (2022)

Cooperation Achieves Results at UNC-CH
por: Eubanks, Mary
Publicado: (2004)

Breathing down the neck of Unc104
por: Wordeman, Linda
Publicado: (2003)

A Systematic Analysis of the Role of Unc-5 Netrin Receptor A (UNC5A) in Human Cancers
por: Zhou, Zonglang, et al.
Publicado: (2022)

UNC-16/JIP3 and UNC-76/FEZ1 limit the density of mitochondria in C. elegans neurons by maintaining the balance of anterograde and retrograde mitochondrial transport
por: Sure, Guruprasada Reddy, et al.
Publicado: (2018)

Expanding the Vision of Environmental Health at UNC-CH
por: Spivey, Angela
Publicado: (2004)

NIEHS, UNC and Duke Instate Training Program
Publicado: (1994)

Interactions between innexins UNC-7 and UNC-9 mediate electrical synapse specificity in the Caenorhabditis elegans locomotory nervous system
por: Starich, Todd A, et al.
Publicado: (2009)

UNC-13L, UNC-13S, and Tomosyn form a protein code for fast and slow neurotransmitter release in Caenorhabditis elegans
por: Hu, Zhitao, et al.
Publicado: (2013)

Regulation of Gap Junction Dynamics by UNC-44/ankyrin and UNC-33/CRMP through VAB-8 in C. elegans Neurons
por: Meng, Lingfeng, et al.
Publicado: (2016)

TOM-1/tomosyn acts with the UNC-6/netrin receptor UNC-5 to inhibit growth cone protrusion in Caenorhabditis elegans
por: Mahadik, Snehal S., et al.
Publicado: (2023)

Sustained expression of unc-4 homeobox gene and unc-37/Groucho in postmitotic neurons specifies the spatial organization of the cholinergic synapses in C. elegans
por: Kurashina, Mizuki, et al.
Publicado: (2021)

Netrin (UNC-6) mediates dendritic self-avoidance
por: Smith, Cody J., et al.
Publicado: (2012)

UCS protein function is partially restored in the Saccharomyces cerevisiae she4 mutant with expression of the human UNC45-GC, but not UNC45-SM
por: Escalante, Susana Gómez, et al.
Publicado: (2017)

UNC79 and UNC80, Putative Auxiliary Subunits of the NARROW ABDOMEN Ion Channel, Are Indispensable for Robust Circadian Locomotor Rhythms in Drosophila
por: Lear, Bridget C., et al.
Publicado: (2013)

Unc-5 homolog B (UNC5B) is one of the key downstream targets of N-α-Acetyltransferase 10 (Naa10)
por: Xu, Huiyu, et al.
Publicado: (2016)

UNC-33L partially rescues life span and locomotion defects in unc-33 mutants but fails to rescue dauer formation defects.
por: Lopez, Melissa E, et al.
Publicado: (2022)

20 Years of unc-119 as a transgene marker
por: Maduro, Morris F
Publicado: (2015)

Validation of the UNC OCT Index for the Diagnosis of Early Glaucoma
por: Mwanza, Jean-Claude, et al.
Publicado: (2018)

Haploinsufficiency of UNC13D increases the risk of lymphoma
por: Löfstedt, Alexandra, et al.
Publicado: (2019)

Endogenous expression of UNC-59/Septin in C. elegans
por: Chen, David D., et al.
Publicado: (2019)

Development of the UNC Perceived Message Effectiveness Scale for Youth
por: Noar, Seth M, et al.
Publicado: (2023)

Investigating the regulation of the unc-33 promoter by environmental stressors
por: Garcia-Gonzalez, Bianca, et al.
Publicado: (2022)

UNC‐120/SRF independently controls muscle aging and lifespan in Caenorhabditis elegans
por: Mergoud dit Lamarche, Adeline, et al.
Publicado: (2018)

Unc-51-like kinase (ULK) complex-independent autophagy induced by hypoxia
por: Feng, Yan, et al.
Publicado: (2018)

The Wnt Frizzled Receptor MOM-5 Regulates the UNC-5 Netrin Receptor through Small GTPase-Dependent Signaling to Determine the Polarity of Migrating Cells
por: Levy-Strumpf, Naomi, et al.
Publicado: (2015)

The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans
por: Su, Cheng-Wen, et al.
Publicado: (2006)

Somatic expression of unc-54 and vha-6 mRNAs declines but not pan-neuronal rgef-1 and unc-119 expression in aging Caenorhabditis elegans
por: Adamla, Frauke, et al.
Publicado: (2015)

A short isoform of the UNC-6/Netrin receptor UNC-5 is required for growth cone polarity and robust growth cone protrusion in Caenorhabditis elegans
por: Mahadik, Snehal S., et al.
Publicado: (2023)

A short isoform of the UNC-6/Netrin receptor UNC-5 is required for growth cone polarity and robust growth cone protrusion in Caenorhabditis elegans
por: Mahadik, Snehal S., et al.
Publicado: (2023)

Synaptic Protein Degradation Controls Sexually Dimorphic Circuits through Regulation of DCC/UNC-40
por: Salzberg, Yehuda, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8sm7uiiin4e1ca3pen5j57qe6a