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Simvastatin Induces Apoptosis of Fibroblast-Like Synoviocytes

BACKGROUND: Statins (3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors) exert favorable effects on lipoprotein metabolism, but appeared to possess anti-inflammatory properties among others, as suggested by their ability to inhibit collagen-induced arthritis in mice. Their activity in fibroblast-li...

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Detalles Bibliográficos
Autores principales: Litinsky, Ira, Golan, Itshak, Yaron, Michael, Yaron, Ilana, Caspi, Dan, Elkayam, Ori
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746119/
https://www.ncbi.nlm.nih.gov/pubmed/19771181
http://dx.doi.org/10.2174/1874312900903010035