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Glypican-1 controls brain size through regulation of fibroblast growth factor signaling in early neurogenesis
BACKGROUND: Cell surface heparan sulfate proteoglycans (HSPGs) act as co-receptors for multiple families of growth factors that regulate animal cell proliferation, differentiation and patterning. Elimination of heparan sulfate during brain development is known to produce severe structural abnormalit...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746204/ https://www.ncbi.nlm.nih.gov/pubmed/19732411 http://dx.doi.org/10.1186/1749-8104-4-33 |