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Glypican-1 controls brain size through regulation of fibroblast growth factor signaling in early neurogenesis
BACKGROUND: Cell surface heparan sulfate proteoglycans (HSPGs) act as co-receptors for multiple families of growth factors that regulate animal cell proliferation, differentiation and patterning. Elimination of heparan sulfate during brain development is known to produce severe structural abnormalit...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746204/ https://www.ncbi.nlm.nih.gov/pubmed/19732411 http://dx.doi.org/10.1186/1749-8104-4-33 |