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Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues

BACKGROUND: It has been well established that prolactin (PRL) signals through the long form of its receptor (PRL-RL) and activates the Jak/Stat pathway for transcription of PRL target genes. However, signaling pathways mediated through the short PRL-R isoform (PRL-RS) remains controversial. Our rece...

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Detalles Bibliográficos
Autores principales: Devi, Y Sangeeta, Shehu, Aurora, Halperin, Julia, Stocco, Carlos, Le, Jamie, Seibold, Anita M, Gibori, Geula
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746216/
https://www.ncbi.nlm.nih.gov/pubmed/19703295
http://dx.doi.org/10.1186/1477-7827-7-87