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Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues
BACKGROUND: It has been well established that prolactin (PRL) signals through the long form of its receptor (PRL-RL) and activates the Jak/Stat pathway for transcription of PRL target genes. However, signaling pathways mediated through the short PRL-R isoform (PRL-RS) remains controversial. Our rece...
Autores principales: | Devi, Y Sangeeta, Shehu, Aurora, Halperin, Julia, Stocco, Carlos, Le, Jamie, Seibold, Anita M, Gibori, Geula |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746216/ https://www.ncbi.nlm.nih.gov/pubmed/19703295 http://dx.doi.org/10.1186/1477-7827-7-87 |
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