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Loss-of-Nkx3.1 Leads to Activation of Discrete Downstream Target Genes during Prostate Tumorigenesis

The expression of NKX3.1, a transcriptional regulator and tumor suppressor gene in prostate cancer, is downregulated during early stages of prostate tumorigenesis. However, little is known of the alterations in gene expression that occur as a result of this event. We combined laser capture microdiss...

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Detalles Bibliográficos
Autores principales: Song, Haengseok, Zhang, Bin, Watson, Mark A., Humphrey, Peter A., Lim, Hyunjung, Milbrandt, Jeffrey
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746257/
https://www.ncbi.nlm.nih.gov/pubmed/19597465
http://dx.doi.org/10.1038/onc.2009.181