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BtubA-BtubB Heterodimer Is an Essential Intermediate in Protofilament Assembly
BACKGROUND: BtubA and BtubB are two tubulin-like genes found in the bacterium Prosthecobacter. Our work and a previous crystal structure suggest that BtubB corresponds to α−tubulin and BtubA to β−tubulin. A 1∶1 mixture of the two proteins assembles into tubulin-like protofilaments, which further agg...
Autores principales: | Sontag, Christopher A., Sage, Harvey, Erickson, Harold P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746283/ https://www.ncbi.nlm.nih.gov/pubmed/19787042 http://dx.doi.org/10.1371/journal.pone.0007253 |
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