Susceptibility of Pancreatic Beta Cells to Fatty Acids Is Regulated by LXR/PPARα-Dependent Stearoyl-Coenzyme A Desaturase

Chronically elevated levels of fatty acids-FA can cause beta cell death in vitro. Beta cells vary in their individual susceptibility to FA-toxicity. Rat beta cells were previously shown to better resist FA-toxicity in conditions that increased triglyceride formation or mitochondrial and peroxisomal...

Descripción completa

Detalles Bibliográficos
Autores principales: Hellemans, Karine H., Hannaert, Jean-Claude, Denys, Bart, Steffensen, Knut R., Raemdonck, Cindy, Martens, Geert A., Van Veldhoven, Paul P., Gustafsson, Jan-Åke, Pipeleers, Daniel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746288/
https://www.ncbi.nlm.nih.gov/pubmed/19787047
http://dx.doi.org/10.1371/journal.pone.0007266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746288/
https://www.ncbi.nlm.nih.gov/pubmed/19787047
http://dx.doi.org/10.1371/journal.pone.0007266

Ejemplares similares