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Negative Feedback Governs Gonadotrope Frequency-Decoding of Gonadotropin Releasing Hormone Pulse-Frequency

The synthesis of the gonadotropin subunits is directed by pulsatile gonadotropin-releasing hormone (GnRH) from the hypothalamus, with the frequency of GnRH pulses governing the differential expression of the common α-subunit, luteinizing hormone β-subunit (LHβ) and follicle-stimulating hormone β-sub...

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Detalles Bibliográficos
Autores principales: Lim, Stefan, Pnueli, Lilach, Tan, Jing Hui, Naor, Zvi, Rajagopal, Gunaretnam, Melamed, Philippa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746289/
https://www.ncbi.nlm.nih.gov/pubmed/19787048
http://dx.doi.org/10.1371/journal.pone.0007244