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Human Regulatory T Cell Suppressive Function Is Independent of Apoptosis Induction in Activated Effector T Cells
BACKGROUND: CD4(+)CD25(+)FOXP3(+) Regulatory T cells (Treg) play a central role in the immune balance to prevent autoimmune disease. One outstanding question is how Tregs suppress effector immune responses in human. Experiments in mice demonstrated that Treg restrict effector T cell (Teff) responses...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746309/ https://www.ncbi.nlm.nih.gov/pubmed/19779623 http://dx.doi.org/10.1371/journal.pone.0007183 |