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Human Regulatory T Cell Suppressive Function Is Independent of Apoptosis Induction in Activated Effector T Cells

BACKGROUND: CD4(+)CD25(+)FOXP3(+) Regulatory T cells (Treg) play a central role in the immune balance to prevent autoimmune disease. One outstanding question is how Tregs suppress effector immune responses in human. Experiments in mice demonstrated that Treg restrict effector T cell (Teff) responses...

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Detalles Bibliográficos
Autores principales:	Vercoulen, Yvonne, Wehrens, Ellen J., van Teijlingen, Nienke H., de Jager, Wilco, Beekman, Jeffrey M., Prakken, Berent J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746309/ https://www.ncbi.nlm.nih.gov/pubmed/19779623 http://dx.doi.org/10.1371/journal.pone.0007183

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