In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer

Ruthenium complexes offer the potential of reduced toxicity, a novel mechanism of action, non-cross resistance and a different spectrum of activity compared to platinum containing compounds. Thirteen novel ruthenium(II) organometallic arene complexes have been evaluated for activity (in vitro and in...

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Detalles Bibliográficos
Autores principales: Aird, R E, Cummings, J, Ritchie, A A, Muir, M, Morris, R E, Chen, H, Sadler, P J, Jodrell, D I
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746580/
https://www.ncbi.nlm.nih.gov/pubmed/12085218
http://dx.doi.org/10.1038/sj.bjc.6600290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746580/
https://www.ncbi.nlm.nih.gov/pubmed/12085218
http://dx.doi.org/10.1038/sj.bjc.6600290

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