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Expression of multidrug resistance-associated protein1,P-glycoprotein, and thymidylate synthase in gastric cancer patients treated with 5-fluorouracil and doxorubicin-based adjuvant chemotherapy after curative resection

Both 5-fluorouracil and doxorubicin are commonly used agents in chemotherapy of gastric cancer in adjuvant setting as well as metastatic disease. In a variety of malignancies, high expression of multidrug resistance-associated protein1 and P-glycoprotein has been associated with resistance to doxoru...

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Detalles Bibliográficos
Autores principales: Choi, J-H, Lim, H-Y, Joo, H J, Kim, H S, Yi, J W, Kim, H C, Cho, Y K, Kim, M W, Lee, K B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746581/
https://www.ncbi.nlm.nih.gov/pubmed/12085207
http://dx.doi.org/10.1038/sj.bjc.6600305