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Development of an in-vitro model system to investigate the mechanism of muscle protein catabolism induced by proteolysis-inducing factor
The mechanism of muscle protein catabolism induced by proteolysis-inducing factor, produced by cachexia-inducing murine and human tumours has been studied in vitro using C(2)C(12) myoblasts and myotubes. In both myoblasts and myotubes protein degradation was enhanced by proteolysis-inducing factor a...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746596/ https://www.ncbi.nlm.nih.gov/pubmed/12085214 http://dx.doi.org/10.1038/sj.bjc.6600236 |