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Treatment of cancer with cryochemotherapy

Cryosurgery employs freezing to destroy solid tumours. However, frozen cells can survive and cause cancer recurrence. Bleomycin, an anticancer drug with a huge intrinsic cytotoxicity is normally not very effective because it is nonpermeant. We report that freezing facilitates bleomycin penetration i...

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Detalles Bibliográficos
Autores principales: Mir, L M, Rubinsky, B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746597/
https://www.ncbi.nlm.nih.gov/pubmed/12085219
http://dx.doi.org/10.1038/sj.bjc.6600306