DNA-catalyzed sequence-specific hydrolysis of DNA

Deoxyribozymes (DNA catalysts) have been reported for cleavage of RNA phosphodiester linkages, but cleaving peptide or DNA phosphodiester linkages is much more challenging. Using in vitro selection, here we identified deoxyribozymes that sequence-specifically hydrolyze DNA with multiple turnover and...

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Detalles Bibliográficos
Autores principales: Chandra, Madhavaiah, Sachdeva, Amit, Silverman, Scott K.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746877/
https://www.ncbi.nlm.nih.gov/pubmed/19684594
http://dx.doi.org/10.1038/nchembio.201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746877/
https://www.ncbi.nlm.nih.gov/pubmed/19684594
http://dx.doi.org/10.1038/nchembio.201

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