Gli1 maintains cell survival by up-regulating IGFBP6 and Bcl-2 through promoter regions in parallel manner in pancreatic cancer cells

BACKGROUND: Aberrant activation of Hedgehog (Hh) signaling pathway has been reported to be related to malignant biological behavior of pancreatic cancer but its mechanism is unclear yet. Since IGF pathway and Bcl-2 family are involved in proliferation and apoptosis of pancreatic cancer cells, we hyp...

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Detalles Bibliográficos
Autores principales: Xu, Xuan-Fu, Guo, Chuan-Yong, Liu, Jun, Yang, Wen-Juan, Xia, Yu-Jing, Xu, Ling, Yu, Yong-Chun, Wang, Xing-Peng
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746911/
https://www.ncbi.nlm.nih.gov/pubmed/19736394
http://dx.doi.org/10.4103/1477-3163.55429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746911/
https://www.ncbi.nlm.nih.gov/pubmed/19736394
http://dx.doi.org/10.4103/1477-3163.55429

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