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Sustained Oscillations of NF-κB Produce Distinct Genome Scanning and Gene Expression Profiles

NF-κB is a prototypic stress-responsive transcription factor that acts within a complex regulatory network. The signaling dynamics of endogenous NF-κB in single cells remain poorly understood. To examine real time dynamics in living cells, we monitored NF-κB activities at multiple timescales using G...

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Detalles Bibliográficos
Autores principales: Sung, Myong-Hee, Salvatore, Luigi, De Lorenzi, Rossana, Indrawan, Anindya, Pasparakis, Manolis, Hager, Gordon L., Bianchi, Marco E., Agresti, Alessandra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747007/
https://www.ncbi.nlm.nih.gov/pubmed/19787057
http://dx.doi.org/10.1371/journal.pone.0007163