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βα-Hairpin Clamps Brace βαβ Modules and Can Make Substantive Contributions to the Stability of TIM Barrel Proteins

Non-local hydrogen bonding interactions between main chain amide hydrogen atoms and polar side chain acceptors that bracket consecutive βα or αβ elements of secondary structure in αTS from E. coli, a TIM barrel protein, have previously been found to contribute 4–6 kcal mol(−1) to the stability of th...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoyan, Kathuria, Sagar V., Vadrevu, Ramakrishna, Matthews, C. Robert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747017/
https://www.ncbi.nlm.nih.gov/pubmed/19787060
http://dx.doi.org/10.1371/journal.pone.0007179