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Evolution and Functional Diversification of the GLI Family of Transcription Factors in Vertebrates

BACKGROUND: In vertebrates the “SONIC HEDGEHOG” signalling pathway has been implicated in cell-fate determination, proliferation and the patterning of many different cell types and organs. As the GLI family members (GLI1, GLI2 and GLI3) are key mediators of hedgehog morphogenetic signals, over the p...

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Detalles Bibliográficos
Autores principales: Abbasi, Amir Ali, Goode, Debbie K., Amir, Saneela, Grzeschik, Karl-Heinz
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747127/
https://www.ncbi.nlm.nih.gov/pubmed/19812723