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Reactions of Cre with Methylphosphonate DNA: Similarities and Contrasts with Flp and Vaccinia Topoisomerase

BACKGROUND: Reactions of vaccinia topoisomerase and the tyrosine site-specific recombinase Flp with methylphosphonate (MeP) substituted DNA substrates, have provided important insights into the electrostatic features of the strand cleavage and strand joining steps catalyzed by them. A conserved argi...

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Detalles Bibliográficos
Autores principales: Ma, Chien-Hui, Kachroo, Aashiq H., Macieszak, Anna, Chen, Tzu-Yang, Guga, Piotr, Jayaram, Makkuni
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747268/
https://www.ncbi.nlm.nih.gov/pubmed/19789629
http://dx.doi.org/10.1371/journal.pone.0007248