Infrequent mutation of the tumour-suppressor gene Smad4 in early-stage colorectal cancer

Smad4 is a candidate tumour-suppressor gene identified recently on chromosome 18q21.1. Both alleles are inactivated in nearly one-half of pancreatic carcinomas, but its role in the tumorigenesis of other tumours is still unknown. The aim of this study was to investigate the potential involvement of...

Descripción completa

Detalles Bibliográficos
Autores principales: Mamot, C, Mild, G, Reuter, J, Laffer, U, Metzger, U, Terracciano, L, Boulay, J-L, Herrmann, R, Rochlitz, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Molecular and Cellular Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747552/
https://www.ncbi.nlm.nih.gov/pubmed/12569386
http://dx.doi.org/10.1038/sj.bjc.6600733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747552/
https://www.ncbi.nlm.nih.gov/pubmed/12569386
http://dx.doi.org/10.1038/sj.bjc.6600733

Ejemplares similares